Acute Renal Failure in Newborns with Birth Asphyxia

Introduction: Perinatal asphyxia is one of the common causes neonatal morbidity and mortality. It can affect almost all body organs most frequently affected are kidneys. Acute Renal Failure commonest renal complication, manifested by changes in urine output blood chemistries.
 Aims: To evaluate function asphyxiated newborns.
 Methods: This cross-sectional study was conducted, from August 2021 to February 2022, on 95 term neonates admitted Neonatal Intensive Care Unit Nepalgunj Medical College, Kohalpur for birth as per World Health Organization definition. All with Hypoxic Ischemic Encephalopathy were staged Sarnat staging. After 48 hours life, sample sent investigations. Urine monitored managed according hospital protocol.
 Results: Male female ratio M:F 1.90:1. Percentage acute failure higher babies grades. seen 12% Grade I, 82% II 100% III. had significant association staging(p<0.05).The means serum creatinine significantly increased increase grades (p<0.05). Mean among III newborns 0.9±0.44, 2.2±.93and 2.9±0.38 mg/dl respectively. urinary decreased (p<0.05) mean 1.5±0.38, 1.3±0.53and 1.1±0.39 ml/kg/hour respectively III.
 Conclusion: Neonates values creatinine. grading